Leonard W. Rozamus

Redesigning an FKBP–ligand interface to generate chemical dimerizers with novel specificity

Tim Clackson, Yang Wu, Leonard W. Rozamus et al. · Proceedings of the National Academy of Sciences · 1998 · 557 citations · Full text

Fkbp–ligand Interface, Protein Assembly, Molecular Biology +19

Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer

Victor M. Rivera, Guangping Gao, Rebecca Grant et al. · Blood · 2004 · 270 citations · Full text

Design, synthesis, and kinetic evaluation of high-affinity FKBP ligands and the X-ray crystal structures of their complexes with FKBP12

Dennis A. Holt, Juan I. Luengo, Dennis S. Yamashita et al. · Journal of the American Chemical Society · 1993 · 203 citations

X-ray Crystallography, Inorganic Chemistry, Crystal Structure +14

Investigating Protein−Ligand Interactions with a Mutant FKBP Possessing a Designed Specificity Pocket

Yang Wu, Leonard W. Rozamus, Surinder S. Narula et al. · Journal of Medicinal Chemistry · 2000 · 92 citations · Full text

Protein Assembly, Hydrophobic Specificity Pocket, Biomolecular Structure Prediction +19

Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface

Juan I. Luengo, Dennis S. Yamashita, Damien J. Dunnington et al. · Chemistry & Biology · 1995 · 41 citations · Full text