Paolo Vignali

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

McLane J. Watson, Paolo Vignali, Steven J. Mullett et al. · Nature · 2021 · 1.2K citations · Full text

Life Sciences, Immunology, Oncology +16

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Nicole E. Scharping, Dayana B. Rivadeneira, Ashley V. Menk et al. · Nature Immunology · 2021 · 852 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Paolo Vignali, Kristin DePeaux, McLane J. Watson et al. · Nature Immunology · 2022 · 250 citations · Full text

Life Sciences, Immunology, Oncology +16

YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity

Xuhao Ni, Jin‐Hui Tao, Joseph Barbi et al. · Cancer Discovery · 2018 · 235 citations · Full text

Life Sciences, Immunology, Oncology +16

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

B. Rhodes Ford, Paolo Vignali, Natalie Rittenhouse et al. · Science Immunology · 2022 · 113 citations · Full text

Medicine, Immunology, Oncology +17