Concepedia
Statistics
Publications
20
Citations
4.3K
H-Index
17
Active since
2012
Affiliations
UPMC Hillman Cancer Center(Current)
University of Pittsburgh
University of Washington
Harvard University
University of California San Diego
Nicole E. Scharping is an author at UPMC Hillman Cancer Center specializing in immunology, life sciences, and oncology.
Publications per year
2012–2025
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion
Nicole E. Scharping, Dayana B. Rivadeneira, Ashley V. Menk et al. · Nature Immunology · 2021 · 852 citations · Full text
Life Sciences, Cell Biology, Immunology +16
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
Nicole E. Scharping, Ashley V. Menk, Rebecca S. Moreci et al. · Immunity · 2016 · 801 citations · Full text
Medicine, Cancer Biology, Oncology +10
Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia
Nicole E. Scharping, Ashley V. Menk, Ryan D. Whetstone et al. · Cancer Immunology Research · 2016 · 509 citations · Full text
Medicine, Oncology, Pharmacology +17
Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions
Ashley V. Menk, Nicole E. Scharping, Rebecca S. Moreci et al. · Cell Reports · 2018 · 493 citations · Full text
Life Sciences, Biochemistry, Cell Biology +17
4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses
Ashley V. Menk, Nicole E. Scharping, Dayana B. Rivadeneira et al. · The Journal of Experimental Medicine · 2018 · 307 citations · Full text
Medicine, Immunology, Oncology +17
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