Kristin DePeaux

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

McLane J. Watson, Paolo Vignali, Steven J. Mullett et al. · Nature · 2021 · 1.1K citations · Full text

Cancer Immunosurveillance, T-regulatory Cell, Immunology +6

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Nicole E. Scharping, Dayana B. Rivadeneira, Ashley V. Menk et al. · Nature Immunology · 2021 · 760 citations · Full text

Continuous Stimulation, Mitochondrial Function, Mitochondrial Dynamic +12

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Paolo Vignali, Kristin DePeaux, McLane J. Watson et al. · Nature Immunology · 2022 · 235 citations · Full text

Cancer Immunosurveillance, T-regulatory Cell, Immunology +8

The Combined Effect of FGFR Inhibition and PD-1 Blockade Promotes Tumor-Intrinsic Induction of Antitumor Immunity

Sangeetha Palakurthi, Mari Kuraguchi, Sima J. Zacharek et al. · Cancer Immunology Research · 2019 · 144 citations

Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance

Dayana B. Rivadeneira, Kristin DePeaux, Yiyang Wang et al. · Immunity · 2019 · 135 citations · Full text

Cancer Immunosurveillance, Oncolytic Viruses, Synthetic Virology +9