B. Rhodes Ford

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Nicole E. Scharping, Dayana B. Rivadeneira, Ashley V. Menk et al. · Nature Immunology · 2021 · 852 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Paolo Vignali, Kristin DePeaux, McLane J. Watson et al. · Nature Immunology · 2022 · 250 citations · Full text

Life Sciences, Immunology, Oncology +16

Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism

Ronal M. Peralta, Bingxian Xie, Konstantinos Lontos et al. · Nature Immunology · 2024 · 142 citations · Full text

Medicine, Immunology, Oncology +17

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

B. Rhodes Ford, Paolo Vignali, Natalie Rittenhouse et al. · Science Immunology · 2022 · 113 citations · Full text

Medicine, Immunology, Oncology +17

Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy

Andrew Frisch, Yiyang Wang, Bingxian Xie et al. · Cell Metabolism · 2025 · 34 citations · Full text

Life Sciences, Immunology, Oncology +16