Polycystin-2 is an intracellular calcium release channel

Peter Koulen, Yiqiang Cai, Lin Geng, +5

Nature Cell Biology

Molecular PhysiologySignal TransductionPhysiologyCellular BiochemistryMedicine +4

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

Bernard Peissel, Hermik Babakhanlou, Anna Pavlova, +5

Nature Genetics

Targetted Pkd1 MutationPancreas DefectsKnockout MouseDevelopmental BiologyPathology +4

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

Guanqing Wu, Glen S. Markowitz, Li Li, +12

Nature Genetics

CardiomyopathyHeart FailureUrologyCardiorenal SyndromesTargeted Mutations +12

Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif

Lin Geng, Dayne Okuhara, Zhiheng Yu, +4

Journal of Cell Science

Environmental SignalingCilial LocalizationMolecular BiologyPathologyCellular Physiology +14

A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation

Sorin V. Fedeles, Xin Tian, Anna‐Rachel Gallagher, +7

Nature Genetics

MedicineGeneticsGenetic EpidemiologyHuman PolymorphismPathology +10

Identification and localization of polycystin, the PKD1 gene product.

Lin Geng, Yoav Segal, Bernard Peissel, +9

Journal of Clinical Investigation

GeneticsRenal PathologyImmunologyRenal InflammationPathology +17

Dynamic heterogeneity and non-Gaussian statistics for acetylcholine receptors on live cell membrane

Wei He, Hao Song, Yun Su, +4

Nature Communications

Distinct Roles of MicroRNA-1 and -499 in Ventricular Specification and Functional Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes

Ji‐Dong Fu, Stephanie N. Rushing, Deborah K. Lieu, +10

PLoS ONE

Calcium Dependence of Polycystin-2 Channel Activity Is Modulated by Phosphorylation at Ser812

Yiqiang Cai, Georgia I. Anyatonwu, Dayne Okuhara, +9

Journal of Biological Chemistry

NeurotransmissionCellular PhysiologyCalcium DependenceSignaling PathwayCell Regulation +16

Distribution and developmentally regulated expression of murine polycystin

Lin Geng, Yoav Segal, Anna Pavlova, +7

American Journal of Physiology-Renal Physiology