Marco De Cecco

L1 drives IFN in senescent cells and promotes age-associated inflammation

Marco De Cecco, Takahiro Ito, Anna P. Petrashen et al. · Nature · 2019 · 1.2K citations

Life Sciences, Cell Biology, Immunology +14

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation

Matthew Simon, Michael Van Meter, Julia Ablaeva et al. · Cell Metabolism · 2019 · 503 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

Marco De Cecco, Steven W. Criscione, Edward Peckham et al. · Aging Cell · 2013 · 465 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues

Marco De Cecco, Steven W. Criscione, Abigail L. Peterson et al. · Aging · 2013 · 386 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels

Claudia C.S. Chini, Thais Peclat, Gina M. Warner et al. · Nature Metabolism · 2020 · 328 citations · Full text

Life Sciences, Immunology, Molecular Biology +17