Jun-ichi Osuga

Sterol Regulatory Element-binding Protein-1 as a Key Transcription Factor for Nutritional Induction of Lipogenic Enzyme Genes

Hitoshi Shimano, Naoya Yahagi, Michiyo Amemiya-Kudo et al. · Journal of Biological Chemistry · 1999 · 687 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +17

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

Jun-ichi Osuga, Shun Ishibashi, Teruaki Oka et al. · Proceedings of the National Academy of Sciences · 2000 · 577 citations

Life Sciences, Endocrinology, Genetics +17

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi et al. · Nature Medicine · 2007 · 553 citations

Life Sciences, Biochemistry, Endocrinology +16

Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter

Tomohiro Yoshikawa, Hitoshi Shimano, Michiyo Amemiya-Kudo et al. · Molecular and Cellular Biology · 2001 · 526 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

Polyunsaturated Fatty Acids Suppress Sterol Regulatory Element-binding Protein 1c Promoter Activity by Inhibition of Liver X Receptor (LXR) Binding to LXR Response Elements

Tomohiro Yoshikawa, Hitoshi Shimano, Naoya Yahagi et al. · Journal of Biological Chemistry · 2002 · 419 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16