Jun-ichi Osuga

Sterol Regulatory Element-binding Protein-1 as a Key Transcription Factor for Nutritional Induction of Lipogenic Enzyme Genes

Hitoshi Shimano, Naoya Yahagi, Michiyo Amemiya-Kudo et al. · Journal of Biological Chemistry · 1999 · 682 citations · Full text

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

Jun-ichi Osuga, Shun Ishibashi, Teruaki Oka et al. · Proceedings of the National Academy of Sciences · 2000 · 577 citations

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi et al. · Nature Medicine · 2007 · 535 citations

Obesity, Metabolic Syndrome, Biochemistry +10

Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter

Tomohiro Yoshikawa, Hitoshi Shimano, Michiyo Amemiya-Kudo et al. · Molecular and Cellular Biology · 2001 · 525 citations · Full text

Polyunsaturated Fatty Acids Suppress Sterol Regulatory Element-binding Protein 1c Promoter Activity by Inhibition of Liver X Receptor (LXR) Binding to LXR Response Elements

Tomohiro Yoshikawa, Hitoshi Shimano, Naoya Yahagi et al. · Journal of Biological Chemistry · 2002 · 417 citations · Full text

Promoter Activity, Pufa Suppression, Fatty Liver Disease +16