Mårten Fryknäs

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

Pádraig D’Arcy, Slavica Brnjic, Maria Hägg Olofsson et al. · Nature Medicine · 2011 · 493 citations

Proteasome Deubiquitinating Activity, Oncology, Medicine +10

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

Xiaonan Zhang, Mårten Fryknäs, E Hernlund et al. · Nature Communications · 2014 · 247 citations · Full text

Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Anna Segerman, Mia Niklasson, Caroline Haglund et al. · Cell Reports · 2016 · 238 citations · Full text

Clonal Variation, Neural Stem Cell, High-grade Gliomas +21

Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system

Henning Karlsson, Mårten Fryknäs, Rolf Larsson et al. · Experimental Cell Research · 2012 · 178 citations

Cancer Drug Activity, Oncology, Medicine +10

Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer

Wojciech Senkowski, Xiaonan Zhang, Maria Hägg Olofsson et al. · Molecular Cancer Therapeutics · 2015 · 146 citations · Full text