David Tatarakis

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Bettina van Lengerich, Lihong Zhan, Dan Xia et al. · Nature Neuroscience · 2023 · 222 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier

Scarlett J. Barker, Mai B. Thayer, Chaeyoung Kim et al. · Science Translational Medicine · 2024 · 119 citations

Pharmacy, Neuroscience, Pharmacology +17

Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes

Jing Guo, Dylan Braun, Gabriel A. Fitzgerald et al. · Cell · 2024 · 83 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution

Nathalie Khoury, Michelle E. Pizzo, Claire B. Discenza et al. · Nature Communications · 2025 · 50 citations · Full text

Pharmacy, Neuroscience, Pharmaceutics +16

Single-cell transcriptomic analysis of zebrafish cranial neural crest reveals spatiotemporal regulation of lineage decisions during development

David Tatarakis, Zixuan Cang, Xiaojun Wu et al. · Cell Reports · 2021 · 41 citations · Full text

Life Sciences, Biology, Developmental Biology +17