Randy Singh Atwal

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Randy Singh Atwal, Jianrun Xia, Deborah Pinchev et al. · Human Molecular Genetics · 2007 · 389 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Kinase inhibitors modulate huntingtin cell localization and toxicity

Randy Singh Atwal, Carly R. Desmond, Nicholas S. Caron et al. · Nature Chemical Biology · 2011 · 243 citations

Life Sciences, Cell Biology, Pharmacology +14

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Alba Di Pardo, Vittorio Maglione, Melanie Alpaugh et al. · Proceedings of the National Academy of Sciences · 2012 · 174 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

Lise N. Munsie, Nicholas S. Caron, Randy Singh Atwal et al. · Human Molecular Genetics · 2011 · 133 citations · Full text

Life Sciences, Cell Biology, Genetics +17

A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

Randy Singh Atwal, Ray Truant · Autophagy · 2008 · 91 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17