The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals

Ray Truant, Bryan R. Cullen

Molecular and Cellular Biology

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, +3

Human Molecular Genetics

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.

Hua Xiao, Angela Pearson, Benoit Coulombe, +7

Molecular and Cellular Biology

Acidic Activation DomainsMolecular RegulationMolecular BiologyTranscriptional RegulationSignaling Pathway +15

Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation

Ray Truant, J Antunović, Jack Greenblatt, +2

Journal of Virology

ImmunologyHepatitis BMolecular BiologyHepatitis B VirusTumor Biology +14

Kinase inhibitors modulate huntingtin cell localization and toxicity

Randy Singh Atwal, Carly R. Desmond, Nicholas S. Caron, +4

Nature Chemical Biology

Signaling PathwayMedicineReceptor Tyrosine KinaseKinase InhibitorsCell Death +3

Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1

Jonathan D. Moore, Jing Yang, Ray Truant, +1

The Journal of Cell Biology

Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein.

Ray Truant, Hua Xiao, C. James Ingles, +1

Journal of Biological Chemistry

Molecular RegulationMolecular BiologyFriend Leukemia VirusTata Box-binding ProteinYeast Tbp +17

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Alba Di Pardo, Vittorio Maglione, Melanie Alpaugh, +8

Proceedings of the National Academy of Sciences

GeneticsNeurochemical BiomarkersMutant HuntingtinAutophagyNeurology +14

Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin

Nicholas S. Caron, Carly R. Desmond, Jianrun Xia, +1

Proceedings of the National Academy of Sciences

Molecular RegulationGeneticsPolyglutamine Domain FlexibilityMolecular BiologyGenomic Mechanism +14

Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-β

Robert A. Fridell, Ray Truant, Leigh Thorne, +2

Journal of Cell Science

Mip ProteinNuclear ImportMolecular RegulationMolecular BiologyProtein Synthesis +21