Jianrun Xia

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

Randy Singh Atwal, Jianrun Xia, Deborah Pinchev et al. · Human Molecular Genetics · 2007 · 387 citations · Full text

Kinase inhibitors modulate huntingtin cell localization and toxicity

Randy Singh Atwal, Carly R. Desmond, Nicholas S. Caron et al. · Nature Chemical Biology · 2011 · 243 citations

Signaling Pathway, Medicine, Receptor Tyrosine Kinase +5

Huntingtin contains a highly conserved nuclear export signal

Jianrun Xia · Human Molecular Genetics · 2003 · 177 citations · Full text

Neurodegenerative Diseases, Cellular Neurobiology, Natural Sciences +10

Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin

Nicholas S. Caron, Carly R. Desmond, Jianrun Xia et al. · Proceedings of the National Academy of Sciences · 2013 · 147 citations · Full text

Molecular Regulation, Genetics, Polyglutamine Domain Flexibility +16

The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal

Tamara Maiuri, Tanya S. Woloshansky, Jianrun Xia et al. · Human Molecular Genetics · 2013 · 132 citations · Full text

Genetics, Signal Recognition, Molecular Biology +19