Melanie Alpaugh

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Alba Di Pardo, Vittorio Maglione, Melanie Alpaugh et al. · Proceedings of the National Academy of Sciences · 2012 · 171 citations · Full text

Genetics, Neurochemical Biomarkers, Mutant Huntingtin +16

N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation

Laura E. Bowie, Tamara Maiuri, Melanie Alpaugh et al. · Proceedings of the National Academy of Sciences · 2018 · 102 citations · Full text

The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson’s disease

Aurélie de Rus Jacquet, Melanie Alpaugh, Hélèna L. Denis et al. · Nature Communications · 2023 · 98 citations · Full text

Disease‐modifying effects of ganglioside GM1 in Huntington's disease models

Melanie Alpaugh, Danny Galleguillos, Juan Forero et al. · EMBO Molecular Medicine · 2017 · 75 citations · Full text

Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms

Maria Masnata, Giacomo Sciacca, Alexander Maxan et al. · Acta Neuropathologica · 2019 · 62 citations · Full text