Siyu Guan

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody

Conrad En Zuo Chan, Shirley G. K. Seah, De Hoe Chye et al. · PLoS ONE · 2021 · 106 citations · Full text

Pharmacy, Immunology, Infectious Diseases +17

Rationally targeted anti-VISTA antibody that blockades the C-C’ loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor growth in an Fc independent manner

Dipti Thakkar, Shalini Paliwal, Bhushan Dharmadhikari et al. · Journal for ImmunoTherapy of Cancer · 2022 · 62 citations · Full text

Medicine, Immunology, Oncology +17

Astaxanthin from <i>Haematococcus pluvialis</i> alleviates obesity by modulating lipid metabolism and gut microbiota in mice fed a high-fat diet

Meng Wang, Haotian Ma, Siyu Guan et al. · Food & Function · 2021 · 58 citations

Life Sciences, Biochemistry, Nutritional Sciences +17

Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction

Lei Li, Fanjian Li, Xuesong Bai et al. · Pharmacological Research · 2023 · 33 citations · Full text

Life Sciences, Immunology, Neuroscience +16

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody

Conrad En Zuo Chan, Shirley G. K. Seah, De Hoe Chye et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 32 citations · Full text

Pharmacy, Immunology, Infectious Diseases +17