Wim Smets

Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization

Frauke Christ, Stephen M. Shaw, Jonas Demeulemeester et al. · Antimicrobial Agents and Chemotherapy · 2012 · 176 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery of Indole Derivatives as Novel and Potent Dengue Virus Inhibitors

Dorothée Bardiot, Mohamed Koukni, Wim Smets et al. · Journal of Medicinal Chemistry · 2018 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacokinetics +13

Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor

Bart Kesteleyn, Jean‐François Bonfanti, Dorothée Bardiot et al. · Journal of Medicinal Chemistry · 2024 · 34 citations

Medicine, Infectious Diseases, Pharmacology +14

A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models

Hanne Hillen, Aurélie Candi, Bart Vanderhoydonck et al. · Molecular Cancer Therapeutics · 2023 · 28 citations · Full text

Medicine, Oncology, Pharmacology +17

Design and synthesis of novel type VI-like β-turn mimetics. Diversity at the i+1 and the i+2 position

Wim M. De Borggraeve, Bie Verbist, Frederik Rombouts et al. · Tetrahedron · 2004 · 24 citations

Pharmacy, Chemistry, Medicinal Chemistry +11