Bart Vanderhoydonck

Synthesis and Evaluation of 5-Substituted 2′-deoxyuridine Monophosphate Analogues As Inhibitors of Flavin-Dependent Thymidylate Synthase in<i>Mycobacterium tuberculosis</i>

Martin Kögler, Bart Vanderhoydonck, Steven De Jonghe et al. · Journal of Medicinal Chemistry · 2011 · 75 citations · Full text

Discovery of 7-<i>N</i>-Piperazinylthiazolo[5,4-<i>d</i>]pyrimidine Analogues as a Novel Class of Immunosuppressive Agents with in Vivo Biological Activity

Miyeon Jang, Lin Yuan, Steven De Jonghe et al. · Journal of Medicinal Chemistry · 2010 · 37 citations

Immunology, Pharmacotherapy, Immunotherapy +19

Synthesis of highly functionalised spiro-indoles by a halogen atom transfer radical cyclization

Christian V. Stevens, Ellen Van Meenen, Yves Eeckhout et al. · Chemical Communications · 2005 · 34 citations

Ring Closure, Chemical Engineering, Cross-coupling Reaction +14

A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models

Hanne Hillen, Aurélie Candi, Bart Vanderhoydonck et al. · Molecular Cancer Therapeutics · 2023 · 21 citations · Full text

Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment <i>in Vivo</i>

James Reuberson, Helen Horsley, Richard J. Franklin et al. · Journal of Medicinal Chemistry · 2018 · 20 citations · Full text

Pharmaceutical Science, Drug Target, Therapeutics +20