Stephen M. Shaw

BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

Bruno Bockorny, Valerya Semenisty, Teresa Macarulla et al. · Nature Medicine · 2020 · 501 citations

Cxcr4 Antagonist, Oncology, Pancreatic Cancer +8

Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization

Frauke Christ, Stephen M. Shaw, Jonas Demeulemeester et al. · Antimicrobial Agents and Chemotherapy · 2012 · 170 citations · Full text

Amiloride blocks lithium entry through the sodium channel thereby attenuating the resultant nephrogenic diabetes insipidus

Marleen L. A. Kortenoeven, Yuedan Li, Stephen M. Shaw et al. · Kidney International · 2009 · 120 citations · Full text

Resultant Nephrogenic Diabetes, Biochemistry, Sodium Homeostasis +11

Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action

Paul Targett‐Adams, Emily J. S. Graham, Jenny Middleton et al. · Journal of Virology · 2011 · 119 citations

Immunology, Molecular Biology, Lipid Droplets +20

The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens.

William E. Biddison, F E Ward, G M Shearer et al. · The Journal of Immunology · 1980 · 112 citations · Full text

Histocompatibility, Self Antigen, Hla Immunogenetics +18