BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

Bruno Bockorny, Valerya Semenisty, Teresa Macarulla, +23

Nature Medicine

Cxcr4 AntagonistOncologyPancreatic CancerGastrointestinal OncologyMedicine +6

Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization

Frauke Christ, Stephen M. Shaw, Jonas Demeulemeester, +8

Antimicrobial Agents and Chemotherapy

Amiloride blocks lithium entry through the sodium channel thereby attenuating the resultant nephrogenic diabetes insipidus

Marleen L. A. Kortenoeven, Yuedan Li, Stephen M. Shaw, +4

Kidney International

Resultant Nephrogenic DiabetesBiochemistrySodium HomeostasisMedicineNatural Sciences +9

Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action

Paul Targett‐Adams, Emily J. S. Graham, Jenny Middleton, +11

Journal of Virology

ImmunologyMolecular BiologyLipid DropletsAntiviral DrugViral Structural Protein +18

The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens.

William E. Biddison, F E Ward, G M Shearer, +1

The Journal of Immunology

HistocompatibilitySelf AntigenHla ImmunogeneticsImmunologyImmunodominance +16

Development of Lithium-Induced Nephrogenic Diabetes Insipidus Is Dissociated from Adenylyl Cyclase Activity

Yuedan Li, Stephen M. Shaw, Erik‐Jan Kamsteeg, +2

Journal of the American Society of Nephrology

Cellular PhysiologyInsulin SignalingRenal FunctionChronic Kidney DiseaseKidney Research +16

Phenotypic and Genetic Variation in the Susceptibility of Haemophilus influenzae Type b to Antibodies to Somatic Antigens

Porter Anderson, A. R. Flesher, Stephen M. Shaw, +1

Journal of Clinical Investigation

The paradox of Hemophilus infuenzae type B bacteremia in the presence of serum bactericidal activity.

Stephen M. Shaw, Arnold L. Smith, Patrick Anderson, +1

Journal of Clinical Investigation

Medical MicrobiologySerum Bactericidal ActivityAntimicrobial SusceptibilityMicrobial DiseaseAntibiotics +8

Alterations in HLA-DP and HLA-DQ Antigen Frequency in Patients with Dermatitis Herpetiformis

Russell P. Hall, Martin E. Sanders, Rene J. Duquesnoy, +2

Journal of Investigative Dermatology

RheumatologyAutoimmune DiseaseAllergyAtopic DermatitisImmunodeficiencies +11

Influenza virus-specific cytotoxic T cells are restricted by multiple HLA-A3-related self antigens: evidence for recognition of distinct self structures in conjunction with different foreign antigens.

William E. Biddison, G M Shearer, Stephen M. Shaw

The Journal of Immunology

VaccinationHistocompatibilityAllergyT CellsHla Immunogenetics +11