MAIT cells are activated during human viral infections

Bonnie van Wilgenburg, Iris Scherwitzl, Edward Hutchinson, +52

Nature Communications

Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus

Steeve Boulant, Paul Targett‐Adams, John McLauchlan

Journal of General Virology

Viral ReplicationSynthetic VirologyMolecular BiologyLipid DropletsViral Structural Protein +18

Hepatitis C Virus Core Protein Induces Lipid Droplet Redistribution in a Microtubule‐ and Dynein‐Dependent Manner

Steeve Boulant, Mark W. Douglas, Laura Moody, +3

Traffic

Viral ReplicationViral PathogenesisImmunologyMolecular BiologyCytoskeleton +16

Structural Determinants That Target the Hepatitis C Virus Core Protein to Lipid Droplets

Steeve Boulant, Roland Montserret, RM Hope, +5

Journal of Biological Chemistry

Virus StructureViral ReplicationProteinlipid InteractionMolecular VirologyBiochemistry +13

Live Cell Analysis and Targeting of the Lipid Droplet-binding Adipocyte Differentiation-related Protein

Paul Targett‐Adams, Doreen Chambers, Sarah Gledhill, +4

Journal of Biological Chemistry

Visualization of Double-Stranded RNA in Cells Supporting Hepatitis C Virus RNA Replication

Paul Targett‐Adams, Steeve Boulant, John McLauchlan

Journal of Virology

Viral ReplicationSystems BiologyRna GenomesViral HepatitisMedicine +12

The Hepatitis C Virus NS4B Protein Can <i>trans</i> -Complement Viral RNA Replication and Modulates Production of Infectious Virus

Daniel M. Jones, Arvind H. Patel, Paul Targett‐Adams, +1

Journal of Virology

Viral ReplicationViral Polymerase MechanismImmunologyMolecular BiologyReplicase Components +19

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A–cyclophilin A interaction to cyclophilin inhibitors

Udayan Chatterji, Precious Lim, Michael Bobardt, +8

Journal of Hepatology

Drug Resistance AnalysisMedicineNs5a–cyclophilin A InteractionImmunologyResistance Mutation (Virology) +3

Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action

Paul Targett‐Adams, Emily J. S. Graham, Jenny Middleton, +11

Journal of Virology

ImmunologyMolecular BiologyLipid DropletsAntiviral DrugViral Structural Protein +18

A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein

Paul Targett‐Adams, Marion McElwee, Ewa Ehrenborg, +2

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

ObesityTranscriptional RegulationSystems BiologyPhysiologyPpar Response Element +7