Dan L. Sackett

Paclitaxel-resistant Human Ovarian Cancer Cells Have Mutant β-Tubulins That Exhibit Impaired Paclitaxel-driven Polymerization

Paraskevi Giannakakou, Dan L. Sackett, Yoon‐Koo Kang et al. · Journal of Biological Chemistry · 1997 · 681 citations · Full text

Nile red as a polarity-sensitive fluorescent probe of hydrophobic protein surfaces

Dan L. Sackett, J. Wolff · Analytical Biochemistry · 1987 · 575 citations

Protein Chemistry, Proteinlipid Interaction, Biochemistry +5

A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

Paraskevi Giannakakou, Rick Gussio, Eva Nogales et al. · Proceedings of the National Academy of Sciences · 2000 · 475 citations

Tubulin Binding, Drug Target, Molecular Biology +19

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

Paraskevi Giannakakou, Dan L. Sackett, Yvona Ward et al. · Nature Cell Biology · 2000 · 360 citations

Cellular Microtubules, Natural Sciences, Cell Interaction +7

Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration

Tatiana K. Rostovtseva, Kely L. Sheldon, Elnaz Hassanzadeh et al. · Proceedings of the National Academy of Sciences · 2008 · 352 citations · Full text

Low Mom Permeability, Cell Physiology, Molecular Physiology +15