NAD ⁺ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Yujun Hou, Sofie Lautrup, Stephanie A. Cordonnier, +10

Proceedings of the National Academy of Sciences

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells

Monica Bodogai, Jennifer O’Connell, Ki H. Kim, +23

Science Translational Medicine

Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells

Monica Bodogai, Kanako Moritoh, Catalina Lee-Chang, +8

Cancer Research

ImmunologyImmune RegulationImmunoeditingImmunotherapyCancer Biology +21

Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity

Catalina Lee-Chang, Monica Bodogai, Kanako Moritoh, +9

Blood

Genetic Background Strongly Modifies the Severity of Symptoms of Hirschsprung Disease, but Not Hearing Loss in Rats Carrying Ednrbsl Mutations

Ruihua Dang, Daisuke Torigoe, Sari Suzuki, +4

PLoS ONE

GeneticsGenetic EpidemiologyPathologyDisease Gene IdentificationClinical Genetics +14

Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers

Catalina Lee-Chang, Monica Bodogai, Kanako Moritoh, +7

The Journal of Immunology

The chicken 2'-5' oligoadenylate synthetase A inhibits the replication of West Nile Virus

Hassan T. Tag-EL-Din-Hassan, Nobuya Sasaki, Kanako Moritoh, +3

PubMed

Tumor-Derived Thymic Stromal Lymphopoietin Expands Bone Marrow B-cell Precursors in Circulation to Support Metastasis

Emeline Ragonnaud, Kanako Moritoh, Monica Bodogai, +9

Cancer Research

Tslpr DeficiencyBone Marrow FailureLymphocyte DevelopmentImmune Cell DevelopmentMedicine +13

Generation of congenic mouse strains by introducing the virus-resistant genes, Mx1 and Oas1b, of feral mouse-derived inbred strain MSM/Ms into the common strain C57BL/6J.

Kanako Moritoh, Hideto Yamauchi, Atsushi ASANO, +8

PubMed

Transgenic Mouse ModelsGeneticsImmunologyViral PathogenesisType 1 +16

Development and Application of West Nile Virus Subgenomic Replicon RNA Expressing Secreted Alkaline Phosphatase

Kanako Moritoh, Akihiko Maeda, Tomohiro Nishino, +2

Journal of Veterinary Medical Science

Viral ReplicationSynthetic VirologyGeneticsCell Culture MediumMolecular Biology +14