Jennifer O’Connell

NAD ⁺ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Yujun Hou, Sofie Lautrup, Stephanie A. Cordonnier et al. · Proceedings of the National Academy of Sciences · 2018 · 465 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells

Monica Bodogai, Jennifer O’Connell, Ki H. Kim et al. · Science Translational Medicine · 2018 · 181 citations · Full text

Life Sciences, Immunology, Microbiology +16

Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism

Isabel González‐Mariscal, Susan M. Krzysik-Walker, Maı̀re E. Doyle et al. · Scientific Reports · 2016 · 98 citations · Full text

Medicine, Endocrinology, Pharmacology +15

Release of insulin produced by the choroid plexis is regulated by serotonergic signaling

Caio Henrique Mazucanti, Qing‐Rong Liu, Doyle Lang et al. · JCI Insight · 2019 · 95 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets

Isabel González‐Mariscal, Rodrigo A. Montoro, Maı̀re E. Doyle et al. · Diabetologia · 2018 · 70 citations · Full text

Medicine, Endocrinology, Pharmacology +17