Concepedia

Timothy Earr

TE

Statistics

Publications

17

Citations

2K

H-Index

14

Active since

2017

Affiliations

Denali Therapeutics (United States)(Current)

University of Minnesota

University of California, San Francisco

Biogen (United States)

German Center for Neurodegenerative Diseases

Timothy Earr is an author at Denali Therapeutics (United States) specializing in neuroscience, molecular neuroscience, and life sciences.

ORCID

Publications per year

2017–2025

17

Publications

17

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

Alicia Nugent, Karin Lin, Bettina van Lengerich et al. · Neuron · 2020 · 748 citations · Full text

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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Todd Logan, Matthew Simon, Gerald Maxwell Cherf et al. · Cell · 2021 · 229 citations · Full text

, , +12

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Bettina van Lengerich, Lihong Zhan, Dan Xia et al. · Nature Neuroscience · 2023 · 222 citations · Full text

, , +17

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice

Julie C. Ullman, Annie Arguello, Jennifer A. Getz et al. · Science Translational Medicine · 2020 · 205 citations

, , +17

Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia

Dan Xia, Steve Lianoglou, Thomas Sandmann et al. · Molecular Neurodegeneration · 2022 · 123 citations · Full text

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