Robert Pelletier

Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: Differential regulation in primary human hepatocytes versus transformed human cells

Zhiyi Zhang, Robert Pelletier, Y. Nancy Wong et al. · Biochemical and Biophysical Research Communications · 2006 · 49 citations

Cytokine, Signal Transduction, Hepatology +10

Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III

Yongchun Shen, Roch P. Boivin, Naoki Yoneda et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 37 citations

Inflammation, Cytokine, Anti-inflammatory +9

Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4

Z.-Y. Zhang, Belinda M. King, Robert Pelletier et al. · Cancer Chemotherapy and Pharmacology · 2008 · 36 citations

Protein Function, Signal Transduction, Biochemistry +7

Dynamics and Location of the Allosteric Midazolam Site in Cytochrome P4503A4 in Lipid Nanodiscs

Michelle Redhair, John C. Hackett, Robert Pelletier et al. · Biochemistry · 2020 · 36 citations · Full text

Molecular Docking, Molecular Pharmacology, Cytochrome P450 3A4 +14

Discovery of a potent, metabolically stabilized resorcylic lactone as an anti-inflammatory lead

Hong Du, Tomohiro Matsushima, Mark R. Spyvee et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 28 citations

Medicinal Chemistry, Anti-inflammatory, Biochemistry +9