Concepedia

Mark R. Spyvee

MR

15

Publications

540

Citations

14

H-Index

1994

Active since

Affiliations

Eisai (United States)(Current)

Eisai (Japan)

University of Oxford

The University of Texas at Austin

Mark R. Spyvee is an author at Eisai (United States) specializing in natural sciences, biochemistry, and organic chemistry.

Top concepts

Publications per year

1994–2013

15

Publications

15

Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo

Marc S. Lamphier, Wanjun Zheng, Eicke Latz et al. · Molecular Pharmacology · 2013 · 139 citations

A novel antagonist of the prostaglandin E<sub>2</sub> EP<sub>4</sub> receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models

Q Chen, Kazuyo Muramoto, Nagashima Masaaki et al. · British Journal of Pharmacology · 2010 · 94 citations · Full text

Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin

Galina Kuznetsov, Karen TenDyke, Murray J. Towle et al. · Molecular Cancer Therapeutics · 2009 · 69 citations · Full text

, , +17

Discovery of a potent, metabolically stabilized resorcylic lactone as an anti-inflammatory lead

Hong Du, Tomohiro Matsushima, Mark R. Spyvee et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 28 citations

, , +9

Concise syntheses of acromelic acid A and allo-acromelic acid A

Jack E. Baldwin, Andrew M. Fryer, Gareth J. Pritchard et al. · Tetrahedron Letters · 1998 · 26 citations

, , +2

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