Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389

Galina Kuznetsov, Murray J. Towle, Hongsheng Cheng, +6

Cancer Research

Potent <i>in vitro</i> and <i>in vivo</i> anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A

Galina Kuznetsov, Qunli Xu, Lori Rudolph-Owen, +17

Molecular Cancer Therapeutics

E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity

Dae‐Shik Kim, Atsushi Endo, Francis G. Fang, +19

ChemMedChem

Systems BiologySignal TransductionMolecular PhysiologyNovel TherapyImmunology +13

A β-Carboline Alkaloid from the Papua New Guinea Marine Sponge <i>Hyrtios reticulatus</i>

Wayne D. Inman, Walter M. Bray, N.C. Gassner, +6

Journal of Natural Products

Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61

Kuan‐Chun Huang, Zhihong Chen, Yimin Jiang, +16

Molecular Cancer Therapeutics

Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin

Galina Kuznetsov, Karen TenDyke, Murray J. Towle, +15

Molecular Cancer Therapeutics

Purified TubulinApoptosisCell DeathCytoskeletonChemical Biology +15

Cytotoxic Triterpenoid Saponins of <i>Albizia </i><i>gummifera</i> from the Madagascar Rain Forest^,1

Shugeng Cao, Andrew Norris, James S. Miller, +7

Journal of Natural Products

Mycoleptodiscins A and B, Cytotoxic Alkaloids from the Endophytic Fungus <i>Mycoleptodiscus</i> sp. F0194

Humberto E. Ortega, Paul R. Graupner, Yumi Asai, +9

Journal of Natural Products

Antiproliferative effects of halichondrin B analog eribulin mesylate (E7389) against paclitaxel-resistant human cancer cells in vitro

Galina Kuznetsov, Karen TenDyke, Melvin J. Yu, +1

Molecular Cancer Therapeutics

Chemoprevention StrategyMicrotubule DynamicsTumor BiologyMedicinal ChemistryOncology +14

Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking

Xingfeng Bao, Wanjun Zheng, Naoko Hata Sugi, +21

Cancer Biology & Therapy

Chemoprevention StrategyCancer BiologyTumor BiologySignaling PathwayReceptor Tyrosine Kinase +15