Kazuhito Naka

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature Medicine · 2006 · 1.3K citations

Reactive Oxygen Species, Medicine, Stem Cell Mobilization +13

DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1

Óscar Fernández-Capetillo, Hua-Tang Chen, Arkady Celeste et al. · Nature Cell Biology · 2002 · 645 citations

Histone Modifications, Chromatin, Genome Instability +10

TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi et al. · Nature · 2010 · 575 citations · Full text

Hematological Malignancy, Medicine, Hematology +4

Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties.

Yasunori Okada, Yukio Gonoji, Kazuhito Naka et al. · Journal of Biological Chemistry · 1992 · 506 citations · Full text

Matrix Metalloproteinase 9, Gelatinase/type Iv Collagenase, Pathology +17

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

Hiroyuki Takai, Kazuhito Naka, Yuki Okada et al. · The EMBO Journal · 2002 · 432 citations · Full text

Genome Instability, Transcriptional Regulation, Signal Transduction +6