Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

Yoshinobu Ichimura, Satoshi Waguri, Yu‐shin Sou, +17

Molecular Cell

Cell AutophagyMitophagySelective AutophagySignal TransductionSignaling Pathway +8

TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, +6

Nature

Hematological MalignancyMedicineHematologyTgf-β–foxo SignallingCell Biology +2

PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ

Yutaka Kurebayashi, Shigenori Nagai, Ai Ikejiri, +9

Cell Reports

Pi3k-akt-mtorc1 AxisMolecular RegulationGeneticsImmunologyImmune Regulation +16

ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia

Liling Wan, Hong Wen, Yuanyuan Li, +15

Nature

Histone ModificationsChromatinHematological MalignancyChromatin RemodelingMixed-phenotype Acute Leukemia +9

Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in <i>NPM1</i> Mutant Leukemia

Michael W.M. Kühn, E Song, Zhaohui Feng, +13

Cancer Discovery

Metabolic regulation of osteoclast differentiation and function

Yoriko Indo, Sunao Takeshita, Kiyo‐aki Ishii, +4

Journal of Bone and Mineral Research

Methyl-Beta-Cyclodextrin Improves Fertilizing Ability of C57BL/6 Mouse Sperm after Freezing and Thawing by Facilitating Cholesterol Efflux from the Cells1

Toru Takeo, Takayuki Hoshii, Yuki Kondo, +5

Biology of Reproduction

FertilityGeneticsReproductive BiologyFertilisationReproductive Biotechnology +15

mTORC1 is essential for leukemia propagation but not stem cell self-renewal

Takayuki Hoshii, Yuko Tadokoro, Kazuhito Naka, +7

Journal of Clinical Investigation

Mtorc1 AffectsMixed-phenotype Acute LeukemiaMtorc1 ActivityImmunologyLeukemia Propagation +16

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

Takayuki Hoshii, Paolo Cifani, Zhaohui Feng, +7

Cell

Non-catalytic FunctionChromatinGenome InstabilityCell RegulationMolecular Biology +4

Cross-species chromatin interactions drive transcriptional rewiring in Epstein–Barr virus–positive gastric adenocarcinoma

Atsushi Okabe, Kie Kyon Huang, Keisuke Matsusaka, +15

Nature Genetics