Keisuke Ito

Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche

Fumio Arai, Atsushi Hirao, Masako Ohmura et al. · Cell · 2004 · 1.9K citations · Full text

Developmental Biology, Medicine, Stem Cell Mobilization +10

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature Medicine · 2006 · 1.3K citations

Reactive Oxygen Species, Medicine, Stem Cell Mobilization +13

Arteriolar niches maintain haematopoietic stem cell quiescence

Yuya Kunisaki, Ingmar Bruns, Christoph Scheiermann et al. · Nature · 2013 · 1.2K citations · Full text

Developmental Biology, Angiogenesis, Medicine +7

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature · 2004 · 1.2K citations

Developmental Biology, Haematopoietic Stem Cells, Medicine +9

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

Keisuke Ito, Arkaitz Carracedo, Dror Weiss et al. · Nature Medicine · 2012 · 705 citations · Full text

Developmental Biology, Epigenetic Regulation, Pml–ppar-δ Pathway +11