Darren Goffin

Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses

Darren Goffin, Megan Allen, Le Zhang et al. · Nature Neuroscience · 2011 · 236 citations · Full text

Life Sciences, Genetics, Molecular Genetics +8

Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice

I-Ting Judy Wang, Megan Allen, Darren Goffin et al. · Proceedings of the National Academy of Sciences · 2012 · 233 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome

Brian S. Johnson, Ying-Tao Zhao, Maria Fasolino et al. · Nature Medicine · 2017 · 123 citations · Full text

Life Sciences, Genetics, Molecular Biology +4

Cellular origins of auditory event-related potential deficits in Rett syndrome

Darren Goffin, Edward S. Brodkin, Julie A. Blendy et al. · Nature Neuroscience · 2014 · 80 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Elevating expression of MeCP2 T158M rescues DNA binding and Rett syndrome–like phenotypes

Janine M. Lamonica, Deborah Y. Kwon, Darren Goffin et al. · Journal of Clinical Investigation · 2017 · 73 citations · Full text

Life Sciences, Genetics, Neuroscience +17