Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

Daniel Franjic, Mario Škarica, Shaojie Ma, +24

Neuron

Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses

Darren Goffin, Megan Allen, Le Zhang, +12

Nature Neuroscience

ChromatinGenome InstabilityDna BindingProtein StabilityGenetic Disorder +10

Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice

Vaidehi Krishnan, Maggie Zi Ying Chow, Zimei Wang, +4

Proceedings of the National Academy of Sciences

A multidimensional coding architecture of the vagal interoceptive system

Qiancheng Zhao, Chuyue Yu, Rui Wang, +4

Nature

Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model

Baohua Liu, Zimei Wang, Le Zhang, +3

Nature Communications

Transcriptomic and clonal characterization of T cells in the human central nervous system

Jenna L. Pappalardo, Le Zhang, Maggie Pecsok, +8

Science Immunology

Modulation of CREB Activity by the Rho GTPase Regulates Cell and Organism Size during Mouse Embryonic Development

Raffaella Sordella, Marie Classon, Kang-Quan Hu, +7

Developmental Cell

Developmental BiologySignal TransductionOrganism SizeCell DevelopmentMorphogenesis +9

Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q

Joshua Spurrier, LaShae Nicholson, Xiaotian T. Fang, +19

Science Translational Medicine

Circulating clonally expanded T cells reflect functions of tumor-infiltrating T cells

Liliana E. Lucca, Pierre‐Paul Axisa, Benjamin Y. Lu, +10

The Journal of Experimental Medicine

Tumor ImmunologyCancer ImmunosurveillanceTumor-exclusive T CellsT CellsT-regulatory Cell +13

Single-cell analysis reveals inflammatory interactions driving macular degeneration

Manik Kuchroo, Marcello DiStasio, Eric Song, +22

Nature Communications