Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

Irina Leonardi, Iris H. Gao, Woan-Yu Lin, +9

Cell

Type 17DysbiosisMucosal ImmunologyHost-microbe InteractionsSocial Behavior +8

Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses

Darren Goffin, Megan Allen, Le Zhang, +12

Nature Neuroscience

ChromatinGenome InstabilityDna BindingProtein StabilityGenetic Disorder +10

Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice

I-Ting Judy Wang, Megan Allen, Darren Goffin, +7

Proceedings of the National Academy of Sciences

Signal Transduction PathwaysAutism Spectrum DisordersEvent-related PotentialsSocial SciencesSignaling Pathway +15

Notch1 Functions as a Tumor Suppressor in a Model of K-ras–Induced Pancreatic Ductal Adenocarcinoma

Linda Hanlon, Jacqueline L. Avila, Renée M. Demarest, +10

Cancer Research

Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling

Megan Allen, Ben Huang, Michael Notaras, +12

Molecular Psychiatry

HuD Promotes BDNF Expression in Brain Neurons via Selective Stabilization of the BDNF Long 3′UTR mRNA

Megan Allen, Clark W. Bird, Wei Feng, +4

PLoS ONE

Disruption of perineuronal nets increases the frequency of sharp wave ripple events

Zhi Yong Sun, P. Lorenzo Bozzelli, Adam Caccavano, +5

Hippocampus

Synaptic TransmissionNeurotransmissionCellular NeurobiologyCellular PhysiologySocial Sciences +20

hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting<i>Gap-43</i>mRNA translation

Kathryn R. Williams, Damian S. McAninch, Snezana Stefanovic, +6

Molecular Biology of the Cell

Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1

Megan Allen, Suhasini Ghosh, Gerard P. Ahern, +3

Scientific Reports

UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function

Michael Notaras, Megan Allen, Francesco Longo, +5

Molecular Psychiatry

Synaptic PlasticityTranscriptional RegulationSignal TransductionMolecular NeuroscienceSignaling Pathway +8