Nichola L. Davies

Design and Structure of Stapled Peptides Binding to Estrogen Receptors

Chris Phillips, Lee R. Roberts, Markus Schade et al. · Journal of the American Chemical Society · 2011 · 248 citations

Life Sciences, Biochemistry, Molecular Biology +17

Expanding the Armory: Predicting and Tuning Covalent Warhead Reactivity

Richard Lonsdale, Jonathan Burgess, Nicola Colclough et al. · Journal of Chemical Information and Modeling · 2017 · 179 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival

Jason G. Kettle, Husam Alwan, Michał Biśta et al. · Journal of Medicinal Chemistry · 2016 · 136 citations · Full text

Medicine, Oncology, Pharmacology +6

The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2<i>H</i>-pyran-4-yl)-1,3-dihydro-2<i>H</i>-imidazo[4,5-<i>c</i>]quinolin-2-one)

Kurt G. Pike, Bernard Barlaam, Elaine Cadogan et al. · Journal of Medicinal Chemistry · 2018 · 116 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS^G12C

Jason G. Kettle, Sharan K. Bagal, Sue Bickerton et al. · Journal of Medicinal Chemistry · 2022 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17