Kazuharu Ozawa

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

Dehua Chui, Hiroshi Tanahashi, Kazuharu Ozawa et al. · Nature Medicine · 1999 · 366 citations

Neurodegenerative Diseases, Alzheimer's Disease, Alzheimer Presenilin 1 +11

Discovery of Tofogliflozin, a Novel <i>C</i>-Arylglucoside with an <i>O</i>-Spiroketal Ring System, as a Highly Selective Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Yoshihito Ohtake, Tsutomu Sato, Takamitsu Kobayashi et al. · Journal of Medicinal Chemistry · 2012 · 165 citations · Full text

Chemical Biology, Pharmaceutical Chemistry, Molecular Pharmacology +16

Tofogliflozin, a Potent and Highly Specific Sodium/Glucose Cotransporter 2 Inhibitor, Improves Glycemic Control in Diabetic Rats and Mice

Masayuki Suzuki, Kiyofumi Honda, Masanori Fukazawa et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 164 citations

Biochemical Evidence for the Long-Tail Form (Aβ1-42/43) of Amyloid β Protein as a Seed Molecule in Cerebral Deposits of Alzheimer′s Disease

Akira Tamaoka, Takashi Kondo, Asano Odaka et al. · Biochemical and Biophysical Research Communications · 1994 · 100 citations

Neurodegenerative Diseases, Long-tail Form, Alzheimer's Disease +10

Deposition of β-Amyloid Subtypes 40 and 42 Differentiates Dementia With Lewy Bodies From Alzheimer Disease

Carol F. Lippa, Kazuharu Ozawa, David Mann et al. · Archives of Neurology · 1999 · 44 citations