Hiroshi Tanahashi

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

Dehua Chui, Hiroshi Tanahashi, Kazuharu Ozawa et al. · Nature Medicine · 1999 · 366 citations

Neurodegenerative Diseases, Alzheimer's Disease, Alzheimer Presenilin 1 +11

A 1.6-Mb P1-Based Physical Map of the Down Syndrome Region on Chromosome 21

Miki Ohira, Hitoshi Ichikawa, Emiko Suzuki et al. · Genomics · 1996 · 81 citations

Down Syndrome, Chromatin, Cytogenetics +10

X11L2, a New Member of the X11 Protein Family, Interacts with Alzheimer's β-Amyloid Precursor Protein

Hiroshi Tanahashi, Takeshi Tabira · Biochemical and Biophysical Research Communications · 1999 · 76 citations

Neurodegenerative Diseases, Protein Function, Molecular Neuroscience +13

A novel method for making nested deletions and its application for sequencing of a 300 kb region of human APP locus

Masahira Hattori, Fujiko Tsukahara, Yoshiaki Furuhata et al. · Nucleic Acids Research · 1997 · 70 citations · Full text

Three novel alternatively spliced isoforms of the human beta-site amyloid precursor protein cleaving enzyme (BACE) and their effect on amyloid beta-peptide production

Hiroshi Tanahashi, Takeshi Tabira · Neuroscience Letters · 2001 · 65 citations

Protein Expression, Protein Assembly, Biochemistry +5