Helen Plant

Paradoxical activation of Raf by a novel Raf inhibitor

Clare A Hall-Jackson, Patrick A. Eyers, Philip P. Cohen et al. · Chemistry & Biology · 1999 · 261 citations · Full text

Biochemistry, Medicine, Novel Raf Inhibitor +6

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

Rachel H. Clare, Catherine Bardelle, Paul Harper et al. · Nature Communications · 2018 · 128 citations · Full text

Discovery of Imidazo[1,2-<i>a</i>]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis

Subramanyam J. Tantry, Shankar D. Markad, Vikas Shinde et al. · Journal of Medicinal Chemistry · 2017 · 121 citations

Bioorganic Chemistry, Antimicrobial Chemotherapy, Chemical Biology +18

Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily

Jonathan D.J. Wrigley, Gérald Gavory, Iain Simpson et al. · ACS Chemical Biology · 2017 · 84 citations · Full text

Aldo-keto Reductase, Immunology, Molecular Biology +19

Diverse Heterocyclic Scaffolds as Allosteric Inhibitors of AKT

Jason G. Kettle, S Brown, Claire Crafter et al. · Journal of Medicinal Chemistry · 2012 · 51 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Downstream Biomarkers +12