Charlotte A. Bartlett

Crystal-structure-based design and synthesis of benz[cd]indole-containing inhibitors of thymidylate synthase

Michael D. Varney, Gifford Marzoni, Cindy Palmer et al. · Journal of Medicinal Chemistry · 1992 · 116 citations

AG337, a novel lipophilic thymidylate synthase inhibitor: in vitro and in vivo preclinical studies

S. E. Webber, Charlotte A. Bartlett, Theodore J. Boritzki et al. · Cancer Chemotherapy and Pharmacology · 1996 · 89 citations

Medicinal Chemistry, Vivo Preclinical Studies, Biochemistry +3

Structure-Based Design of Substituted Diphenyl Sulfones and Sulfoxides as Lipophilic Inhibitors of Thymidylate Synthase

Terence R. Jones, Stephen E. Webber, Michael D. Varney et al. · Journal of Medicinal Chemistry · 1997 · 43 citations · Full text

Combinatorial Chemistry, Pharmaceutical Science, Phenyl Phenyl Sulfone +18

Protein Structure-Based Design, Synthesis, and Biological Evaluation of 5-Thia-2,6-diamino-4(3<i>H</i>)-oxopyrimidines:  Potent Inhibitors of Glycinamide Ribonucleotide Transformylase with Potent Cell Growth Inhibition

Michael D. Varney, Cindy Palmer, William H. Romines et al. · Journal of Medicinal Chemistry · 1997 · 38 citations · Full text

Structure-Based Design of Lipophilic Quinazoline Inhibitors of Thymidylate Synthase

Terence R. Jones, Michael D. Varney, Stephen E. Webber et al. · Journal of Medicinal Chemistry · 1996 · 34 citations