Concepedia

AG337, a novel lipophilic thymidylate synthase inhibitor: in vitro and in vivo preclinical studies

S. E. Webber, Charlotte A. Bartlett, Theodore J. Boritzki, Jill A. Hilliard, Eleanor F. Howland, Amanda Johnston, Maha Kosa, Stephen A. Margosiak, Cathy A. Morse, Bhasker V. Shetty

Cancer Chemotherapy and Pharmacology · 1996 · 91 citations · 18 references

DOI

Concepts

References

18

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study.

A.L. Jackman, G A Taylor, William Gibson et al. · PubMed · 1991 · 359 citations

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A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleoside triphosphates in cell extracts

Charles Garrett, Daniel V. Santi · Analytical Biochemistry · 1979 · 269 citations

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Allosteric regulation of calf thymus ribonucleoside diphosphate reductase

Staffan Eriksson, Lars Thelander, Margareta Akerman · Biochemistry · 1979 · 187 citations

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Design of thymidylate synthase inhibitors using protein crystal structures: the synthesis and biological evaluation of a novel class of 5-substituted quinazolinones

Stephen E. Webber, Ted M. Bleckman, John J. Attard et al. · Journal of Medicinal Chemistry · 1993 · 161 citations · Full text

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