Theodore J. Boritzki

Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity:  Design, Synthesis, and X-ray Cocrystal Structure

Stacie S. Canan Koch, Lars Thoresen, Jayashree Tikhe et al. · Journal of Medicinal Chemistry · 2002 · 134 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Parp-1 Protein +18

Inhibition of type II topoisomerase by fostriecin

Theodore J. Boritzki, Tammy S. Wolfard, Judith A. Besserer et al. · Biochemical Pharmacology · 1988 · 118 citations

Type Ii Topoisomerase, Medicine, Pharmacology +3

Purine and pyrimidine nucleotide patterns of normal, differentiating, and regenerating liver and of hepatomas in rats.

Robert Jackson, May S. Lui, Theodore J. Boritzki et al. · PubMed · 1980 · 104 citations

Hepatic Disorders, Hepatotoxicity, Metabolism +17

Biochemical pharmacology of the lipophilic antifolate, trimetrexate

Robert Jackson, David W. Fry, Theodore J. Boritzki et al. · Advances in Enzyme Regulation · 1984 · 94 citations

Molecular Pharmacology, Medicinal Chemistry, Biochemical Pharmacology +9

AG337, a novel lipophilic thymidylate synthase inhibitor: in vitro and in vivo preclinical studies

S. E. Webber, Charlotte A. Bartlett, Theodore J. Boritzki et al. · Cancer Chemotherapy and Pharmacology · 1996 · 89 citations

Medicinal Chemistry, Vivo Preclinical Studies, Biochemistry +3