Jayashree Tikhe

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

David A. Matthews, Peter S. Dragovich, S. E. Webber et al. · Proceedings of the National Academy of Sciences · 1999 · 318 citations · Full text

Life Sciences, Biochemistry, Biology +17

Design, Synthesis, and Evaluation of Nonpeptidic Inhibitors of Human Rhinovirus 3C Protease

Stephen E. Webber, Jayashree Tikhe, Stephen T. Worland et al. · Journal of Medicinal Chemistry · 1996 · 145 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +16

Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity:  Design, Synthesis, and X-ray Cocrystal Structure

Stacie S. Canan Koch, Lars Thoresen, Jayashree Tikhe et al. · Journal of Medicinal Chemistry · 2002 · 138 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies

Peter S. Dragovich, Stephen E. Webber, Robert E. Babine et al. · Journal of Medicinal Chemistry · 1998 · 111 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies

Peter S. Dragovich, Stephen E. Webber, Robert E. Babine et al. · Journal of Medicinal Chemistry · 1998 · 92 citations

Pharmacy, Infectious Diseases, Medicinal Chemistry +15