William H. Romines

AG2034: a novel inhibitor of glycinamide ribonucleotide formyltransferase

Theodore J. Boritzki, Charlotte A. Barlett, Cathy Zhang et al. · Investigational New Drugs · 1996 · 62 citations

Biochemistry, Glycobiology, Oligonucleotide +2

Protein Structure-Based Design, Synthesis, and Biological Evaluation of 5-Thia-2,6-diamino-4(3<i>H</i>)-oxopyrimidines:  Potent Inhibitors of Glycinamide Ribonucleotide Transformylase with Potent Cell Growth Inhibition

Michael D. Varney, Cindy Palmer, William H. Romines et al. · Journal of Medicinal Chemistry · 1997 · 38 citations · Full text

Crystal-Structure-Based Design and Synthesis of Novel C-Terminal Inhibitors of HIV Protease

Michael D. Varney, Krzysztof Appelt, Vincent J. Kalish et al. · Journal of Medicinal Chemistry · 1994 · 30 citations · Full text

Synthesis and biological evaluation of ‐<i>n</i>[4‐(2‐<i>trans</i>‐[([2,6‐diamino‐4(3<i>H</i>)‐oxopyrimidin‐5‐yl]methyl)thio]cyclobutyl)benzoyl] ‐l‐glutamic acid a novel 5‐thiapyrimidinone inhibitor of dihydrofolate reductase

Michael D. Varney, William H. Romines, Theodore J. Boritzki et al. · Journal of Heterocyclic Chemistry · 1995 · 12 citations

Inhibitory Activity, Medicinal Chemistry, Biosynthesis +15