John C. Manteiga

Coactivator condensation at super-enhancers links phase separation and gene control

Benjamin R. Sabari, Alessandra Dall’Agnese, Ann Boija et al. · Science · 2018 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +17

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

Ann Boija, Isaac A. Klein, Benjamin R. Sabari et al. · Cell · 2018 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

Yang Guo, John C. Manteiga, Jonathan E. Henninger et al. · Nature · 2019 · 722 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Partitioning of cancer therapeutics in nuclear condensates

Isaac A. Klein, Ann Boija, Lena K. Afeyan et al. · Science · 2020 · 524 citations · Full text

Natural Sciences, Cancer Biology, Oncology +17

Engineered Cpf1 variants with altered PAM specificities

Linyi Gao, David Cox, Winston X. Yan et al. · Nature Biotechnology · 2017 · 470 citations · Full text

Engineering, Bioengineering, Molecular Biology +6