Concepedia

Lena K. Afeyan

LK

12

Publications

3.9K

Citations

12

H-Index

2018

Active since

Affiliations

Massachusetts Institute of Technology(Current)

Whitehead Institute for Biomedical Research

Dana-Farber Cancer Institute

Harvard University

University of Colorado Boulder

Lena K. Afeyan is an author at Massachusetts Institute of Technology specializing in medicine, cell biology, and gene expression.

Top concepts

MedicineCell BiologyGene ExpressionGene RegulationTranscriptional RegulationGeneticsChromatinSystems BiologyNatural SciencesFunctional Genomics

Publications per year

2018–2025

12

Publications

12

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

Ann Boija, Isaac A. Klein, Benjamin R. Sabari et al. · Cell · 2018 · 1.8K citations · Full text

Chromatin, Transcriptional Regulation, Functional Genomics +13

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

Yang Guo, John C. Manteiga, Jonathan E. Henninger et al. · Nature · 2019 · 687 citations · Full text

Transcriptional Regulation, Signal Transduction, Natural Sciences +10

Partitioning of cancer therapeutics in nuclear condensates

Isaac A. Klein, Ann Boija, Lena K. Afeyan et al. · Science · 2020 · 505 citations · Full text

Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes

Alicia V. Zamudio, Alessandra Dall’Agnese, Jonathan E. Henninger et al. · Molecular Cell · 2019 · 292 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +10

MeCP2 links heterochromatin condensates and neurodevelopmental disease

Charles H. Li, Eliot L. Coffey, Alessandra Dall’Agnese et al. · Nature · 2020 · 195 citations · Full text

Chromatin, Developmental Biology, Chromatin Structure +9

Rows per page

1–5 of 12