Zhaomin Liu

A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

Longchuan Bai, Haibin Zhou, Renqi Xu et al. · Cancer Cell · 2019 · 618 citations · Full text

Medicine, Molecular Biology, Oncology +7

Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER)

Jiantao Hu, Biao Hu, Mingliang Wang et al. · Journal of Medicinal Chemistry · 2019 · 271 citations

Life Sciences, Medicinal Chemistry, Oncology +13

Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein

Haibin Zhou, Longchuan Bai, Renqi Xu et al. · Journal of Medicinal Chemistry · 2019 · 213 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +12

Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders

Jiuling Yang, Yangbing Li, Angelo Aguilar et al. · Journal of Medicinal Chemistry · 2019 · 173 citations · Full text

Life Sciences, Molecular Biology, Oncology +7

Chiral Counteranion Synergistic Organocatalysis under High Temperature: Efficient Construction of Optically Pure Spiro[cyclohexanone-oxindole] Backbone

Yu‐Bao Lan, Hua Zhao, Zhaomin Liu et al. · Organic Letters · 2011 · 153 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16