Pui Yee Ng

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Medicine, Medicinal Chemistry, Molecular Biology +14

AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer

Joanna C. Chan, Katherine M. Hannan, Kim Riddell et al. · Science Signaling · 2011 · 238 citations

Life Sciences, Cancer Biology, Molecular Biology +16

Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

Han Dai, April Case, Thomas V. Riera et al. · Nature Communications · 2015 · 203 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Strained Silacycles in Organic Synthesis:  A New Reagent for the Enantioselective Allylation of Aldehydes

James W. A. Kinnaird, Pui Yee Ng, Katsumi Kubota et al. · Journal of the American Chemical Society · 2002 · 178 citations

Natural Sciences, Chemistry, Catalysis +10

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

Jennifer R. Devlin, Katherine M. Hannan, Nadine Hein et al. · Cancer Discovery · 2015 · 127 citations · Full text

Life Sciences, Oncology, Pharmacology +17