Paul Renauer

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Matthew B. Dong, Guangchuan Wang, Ryan D. Chow et al. · Cell · 2019 · 308 citations · Full text

Off-target Effect, Genome Surgery, Cd8 T Cells +11

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

Ryan D. Chow, Christopher D. Guzman, Guangchuan Wang et al. · Nature Neuroscience · 2017 · 243 citations · Full text

Off-target Effect, Glioma, Genome Engineering +8

IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus

Ming Zhao, Yin Zhou, Bochen Zhu et al. · Annals of the Rheumatic Diseases · 2016 · 223 citations · Full text

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells

Patrick Coit, Paul Renauer, Matlock A. Jeffries et al. · Journal of Autoimmunity · 2015 · 137 citations · Full text

Glomerulonephritis, Autoimmune Disease, Systemic Lupus Erythematosus Treatment +11

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade

Guangchuan Wang, Ryan D. Chow, Lvyun Zhu et al. · Cancer Discovery · 2020 · 133 citations · Full text