PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Sven Geisler, Kira M. Holmström, Diana Skujat, +4

Nature Cell Biology

Cell AutophagyMitophagyAutophagyCell DeathPink1/parkin-mediated Mitophagy +3

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

Kamran Ghoreschi, Jürgen Brück, Christina Kellerer, +17

The Journal of Experimental Medicine

Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair

Oliver C. Rothfuss, Heike Fischer, Takafumi Hasegawa, +8

Human Molecular Genetics

Mitochondrial Dna RepairMitophagyProtein Quality ControlNeurodegenerative DiseasesMitochondrial Biogenesis +8

Analysis of differential DNA damage in the mitochondrial genome employing a semi-long run real-time PCR approach

Oliver C. Rothfuss, Thomas Gasser, Nadja Patenge

Nucleic Acids Research

Dna DamageGeneticsDna AnalysisMolecular BiologyMolecular Genetics +21

<i>SOX2</i> Expression Associates with Stem Cell State in Human Ovarian Carcinoma

Petra M. Bareiss, Anna Paczulla, Hui Wang, +15

Cancer Research

Stem Cell BiologyCancer BiologyTumor BiologyOvarian CancerCancer Cell Biology +15

High Glutathione and Glutathione Peroxidase-2 Levels Mediate Cell-Type-Specific DNA Damage Protection in Human Induced Pluripotent Stem Cells

Benjamin Dannenmann, Simon Lehle, Dominic G. Hildebrand, +7

Stem Cell Reports

Nuclear Dna LesionsInduced Pluripotent Stem CellDna DamagePluripotent Stem CellsGlutathione Impaired Protection +13

IκBζ Is a Transcriptional Key Regulator of CCL2/MCP-1

Dominic G. Hildebrand, Eva Alexander, Sebastian Hörber, +10

The Journal of Immunology

Sulforaphane Protects from T Cell–Mediated Autoimmune Disease by Inhibition of IL-23 and IL-12 in Dendritic Cells

Julia Geisel, Jürgen Brück, Ivana Glocova, +7

The Journal of Immunology

ImmunologyImmune RegulationImmunologic MechanismSfn-treated DcsCd4 T Cell Responses +24

Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level

Vilma Graupner, E. A. Alexander, Tim Overkamp, +5

Cell Death and Differentiation

Signal TransductionSignaling PathwayCell RegulationNatural SciencesMolecular Biology +8

LORD-Q: a long-run real-time PCR-based DNA-damage quantification method for nuclear and mitochondrial genome analysis

Simon Lehle, Dominic G. Hildebrand, Britta Merz, +5

Nucleic Acids Research

Dna DamageGeneticsDna AnalysisMolecular BiologyGenomics +17