Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

Zheng Hu, Da Zhu, Wei Wang, +33

Nature Genetics

Functional GenomicsCervical CancerEngineeringHuman Papillomavirus VaccinesCervical Cancer Identifies +10

Disruption of HPV16-E7 by CRISPR/Cas System Induces Apoptosis and Growth Inhibition in HPV16 Positive Human Cervical Cancer Cells

Zheng Hu, Lan Yu, Da Zhu, +11

BioMed Research International

EngineeringCervical CancerCancer-associated VirusHuman Papillomavirus VaccinesMedicine +13

<i>SOX2</i> Expression Associates with Stem Cell State in Human Ovarian Carcinoma

Petra M. Bareiss, Anna Paczulla, Hui Wang, +15

Cancer Research

Stem Cell BiologyCancer BiologyTumor BiologyOvarian CancerCancer Cell Biology +15

CRISPR/Cas9 mediated G4946E substitution in the ryanodine receptor of Spodoptera exigua confers high levels of resistance to diamide insecticides

Yayun Zuo, Hui Wang, Yanjun Xu, +4

Insect Biochemistry and Molecular Biology

BiologyNatural SciencesGeneticsEntomologyRyanodine Receptor +9

Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer

Liyuan Zhou, Qiongzi Qiu, Qing Zhou, +11

Nature Communications

Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells

Sumitava Dastidar, Simon Ardui, Kshitiz Singh, +20

Nucleic Acids Research

Hearing of Otof-deficient mice restored by trans-splicing of N- and C-terminal otoferlin

Honghai Tang, Hui Wang, Shengyi Wang, +10

Human Genetics

C-terminal OtoferlinDevelopmental BiologyOtof-deficient MiceAudiologyAuditory Physiology +8

An Efficient CRISPR/Cas9 Platform for Rapidly Generating Simultaneous Mutagenesis of Multiple Gene Homoeologs in Allotetraploid Oilseed Rape

Chao Li, Mengyu Hao, Wenxiang Wang, +7

Frontiers in Plant Science

Sine oculis homeobox homolog 1 promotes DNA replication and cell proliferation in cervical cancer

Dan Liu, Xiaoxue Zhang, Bixin Xi, +7

International Journal of Oncology

GeneticsMolecular BiologyCell ProliferationCell CycleCancer Biology +14

HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer

Canhui Cao, Ping Hong, Xingyu Huang, +24

Journal of genetics and genomics/Journal of Genetics and Genomics

Three-dimensional Genome StructureMolecular BiologyPathologyEpigeneticsCancer-associated Virus +15