Shinichi Masada

Discovery of [<i>cis</i>-3-({(5<i>R</i>)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1<i>H</i>-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5<i>H</i>)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist

Mitsunori Kono, Atsuko Ochida, Tsuneo Oda et al. · Journal of Medicinal Chemistry · 2018 · 62 citations

Pharmacotherapy, Pharmaceutical Chemistry, Pre-clinical Pharmacology +16

Melanin-Concentrating Hormone Receptor 1 Antagonists. Synthesis and Structure–Activity Relationships of Novel 3-(Aminomethyl)quinolines

Makoto Kamata, Toshiro Yamashita, Toshihiro Imaeda et al. · Journal of Medicinal Chemistry · 2012 · 31 citations · Full text

Discovery of orally efficacious RORγt inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds

Junya Shirai, Yoshihide Tomata, Mitsunori Kono et al. · Bioorganic & Medicinal Chemistry · 2017 · 23 citations · Full text

Medicinal Chemistry, Part 1, Lead Scaffolds +11

Synthesis, Structure–Activity Relationship, and Pharmacological Studies of Novel Melanin-Concentrating Hormone Receptor 1 Antagonists 3-Aminomethylquinolines: Reducing Human Ether-a-go-go-Related Gene (hERG) Associated Liabilities

Shizuo Kasai, Makoto Kamata, Shinichi Masada et al. · Journal of Medicinal Chemistry · 2012 · 19 citations · Full text

Structure–activity Relationship, Food Intake, Pharmacotherapy +17

Discovery of 3,5-Diphenyl-4-methyl-1,3-oxazolidin-2-ones as Novel, Potent, and Orally Available Δ-5 Desaturase (D5D) Inhibitors

Jun Fujimoto, Rei Okamoto, Naoyoshi Noguchi et al. · Journal of Medicinal Chemistry · 2017 · 18 citations · Full text

Available δ-5 Desaturase, Drug Target, Pharmacotherapy +17