Peter D. Craggs

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Huw D. Lewis, John Liddle, Jim Coote et al. · Nature Chemical Biology · 2015 · 717 citations · Full text

BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models

Anastasia Wyce, Gopinath Ganji, Kimberly N. Smitheman et al. · PLoS ONE · 2013 · 203 citations · Full text

Mycn Copy Number, Bet Family Proteins, Cell Regulation +14

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael G. Thomas et al. · Proceedings of the National Academy of Sciences · 2019 · 165 citations · Full text

Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe

P. G. Humphreys, Paul Bamborough, Chun‐wa Chung et al. · Journal of Medicinal Chemistry · 2016 · 97 citations · Full text

Molecular Regulation, Immunology, Immunotherapeutics +22

1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain

Emmanuel H. Demont, Paul Bamborough, Chun‐wa Chung et al. · ACS Medicinal Chemistry Letters · 2014 · 88 citations · Full text

Protein Assembly, Molecular Biology, Pharmacotherapy +21